Ubiquitination mediates Kv1.3 endocytosis as a mechanism for protein kinase C-dependent modulation

The voltage-dependent potassium channel Kv1.3 plays essential physiological functions in the immune system. Kv1.3, regulating the membrane potential, facilitates downstream Ca(2+) -dependent pathways and becomes concentrated in specific membrane microdomains that serve as signaling platforms. Increa...

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Detalles Bibliográficos
Autores principales: Martínez-Mármol, Ramón, Styrczewska, Katarzyna, Pérez-Verdaguer, Mireia, Vallejo-Gracia, Albert, Comes, Núria, Sorkin, Alexander, Felipe, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301257/
https://www.ncbi.nlm.nih.gov/pubmed/28186199
http://dx.doi.org/10.1038/srep42395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301257/
https://www.ncbi.nlm.nih.gov/pubmed/28186199
http://dx.doi.org/10.1038/srep42395

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