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Combined effect of BCG vaccination and enriched environment promote neurogenesis and spatial cognition via a shift in meningeal macrophage M2 polarization

BACKGROUND: The spatial learning abilities of developing mice benefit from extrinsic cues, such as an enriched environment, with concomitant enhancement in cognitive functions. Interestingly, such enhancements can be further increased through intrinsic Bacillus Calmette-Guérin (BCG) vaccination. RES...

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Detalles Bibliográficos
Autores principales: Qi, Fangfang, Zuo, Zejie, Yang, Junhua, Hu, Saisai, Yang, Yang, Yuan, Qunfang, Zou, Juntao, Guo, Kaihua, Yao, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301319/
https://www.ncbi.nlm.nih.gov/pubmed/28183352
http://dx.doi.org/10.1186/s12974-017-0808-7