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Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model

This study was aimed to evaluate the effects of celastrol, a natural compound with multiple bioactivities, on multiple sclerosis and optic neuritis (ON) in rat experimental autoimmune encephalomyelitis (EAE). EAE was induced in Sprague Dawley rats using myelin basic protein, and the animals received...

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Detalles Bibliográficos
Autores principales: Yang, Hongbin, Liu, Chang, Jiang, Jie, Wang, Yuena, Zhang, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301323/
https://www.ncbi.nlm.nih.gov/pubmed/28239352
http://dx.doi.org/10.3389/fphar.2017.00044