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Virulence Inhibitors from Brazilian Peppertree Block Quorum Sensing and Abate Dermonecrosis in Skin Infection Models

Widespread antibiotic resistance is on the rise and current therapies are becoming increasingly limited in both scope and efficacy. Methicillin-resistant Staphylococcus aureus (MRSA) represents a major contributor to this trend. Quorum sensing controlled virulence factors include secreted toxins res...

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Detalles Bibliográficos
Autores principales: Muhs, Amelia, Lyles, James T., Parlet, Corey P., Nelson, Kate, Kavanaugh, Jeffery S., Horswill, Alexander R., Quave, Cassandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301492/
https://www.ncbi.nlm.nih.gov/pubmed/28186134
http://dx.doi.org/10.1038/srep42275