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A novel ECG analog 4-(S)-(2,4,6-trimethylthiobenzyl)-epigallocatechin gallate selectively induces apoptosis of B16-F10 melanoma via activation of autophagy and ROS

Autophagy-induced cancer cell death has become a novel strategy for the development of cancer therapeutic drugs. Numerous studies have indicated that green tea polyphenols induce both autophagy and apoptosis in a variety of cancer cells. Here, we synthesized a series of green tea polyphenol analogue...

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Detalles Bibliográficos
Autores principales: Xie, Jing, Yun, Ju-ping, Yang, Ya-nan, Hua, Fang, Zhang, Xiao-wei, Lin, Heng, Lv, Xiao-xi, Li, Ke, Zhang, Pei-cheng, Hu, Zhuo-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301500/
https://www.ncbi.nlm.nih.gov/pubmed/28186123
http://dx.doi.org/10.1038/srep42194