P2X7 Receptor Mediates Spinal Microglia Activation of Visceral Hyperalgesia in a Rat Model of Chronic Pancreatitis

BACKGROUND & AIMS: Molecular mechanisms underlying the activated spinal microglia in association with the pain in chronic pancreatitis (CP) remain unknown. We tested whether P2X7R on spinal microglia mediates the pathogenesis of visceral pain using a CP rat model. METHODS: The CP model was induc...

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Detalles Bibliográficos
Autores principales: Liu, Pei-Yi, Lee, I-Hui, Tan, Ping-Heng, Wang, Yen-Po, Tsai, Chia-Fen, Lin, Han-Chieh, Lee, Fa-Yauh, Lu, Ching-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301503/
https://www.ncbi.nlm.nih.gov/pubmed/28210704
http://dx.doi.org/10.1016/j.jcmgh.2015.07.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301503/
https://www.ncbi.nlm.nih.gov/pubmed/28210704
http://dx.doi.org/10.1016/j.jcmgh.2015.07.008

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