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Inhibition of prolyl 4-hydroxylase decreases muscle fibrosis following chronic rotator cuff tear

OBJECTIVES: Rotator cuff tears are among the most frequent upper extremity injuries. Current treatment strategies do not address the poor quality of the muscle and tendon following chronic rotator cuff tears. Hypoxia-inducible factor-1 alpha (HIF-1α) is a transcription factor that activates many gen...

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Detalles Bibliográficos
Autores principales: Gumucio, J. P., Flood, M. D., Bedi, A., Kramer, H. F., Russell, A. J., Mendias, C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301902/
https://www.ncbi.nlm.nih.gov/pubmed/28108482
http://dx.doi.org/10.1302/2046-3758.61.BJR-2016-0232.R1