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Inhibition of prolyl 4-hydroxylase decreases muscle fibrosis following chronic rotator cuff tear
OBJECTIVES: Rotator cuff tears are among the most frequent upper extremity injuries. Current treatment strategies do not address the poor quality of the muscle and tendon following chronic rotator cuff tears. Hypoxia-inducible factor-1 alpha (HIF-1α) is a transcription factor that activates many gen...
Autores principales: | Gumucio, J. P., Flood, M. D., Bedi, A., Kramer, H. F., Russell, A. J., Mendias, C. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301902/ https://www.ncbi.nlm.nih.gov/pubmed/28108482 http://dx.doi.org/10.1302/2046-3758.61.BJR-2016-0232.R1 |
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