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Self-optimisation and model-based design of experiments for developing a C–H activation flow process
A recently described C(sp(3))–H activation reaction to synthesise aziridines was used as a model reaction to demonstrate the methodology of developing a process model using model-based design of experiments (MBDoE) and self-optimisation approaches in flow. The two approaches are compared in terms of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301945/ https://www.ncbi.nlm.nih.gov/pubmed/28228856 http://dx.doi.org/10.3762/bjoc.13.18 |