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A postsynthetically 2’-“clickable” uridine with arabino configuration and its application for fluorescent labeling and imaging of DNA

The arabino-configured analog of uridine with a propargyl group at the 2’-position was synthesized and incorporated into DNA by solid-phase chemistry. The fluorescence quantum yields of DNA strands that were postsynthetically modified by blue and green emitting cyanine-styryl dyes were improved due...

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Detalles Bibliográficos
Autores principales: Walter, Heidi-Kristin, Olshausen, Bettina, Schepers, Ute, Wagenknecht, Hans-Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302004/
https://www.ncbi.nlm.nih.gov/pubmed/28228854
http://dx.doi.org/10.3762/bjoc.13.16