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Troponin Mutation Caused Diastolic Dysfunction and Experimental Treatment in Transgenic Mice with Cardiomyopathy
Troponin, a contractile protein of the thin filament of striated muscle, consists of three subunits: troponin C (TnC), troponin T (TnT), and troponin I (TnI). Cardiac troponin I (cTnI) plays a critical role in regulation of cardiac function. The physiological effect of cTnI, as an inhibitory subunit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Global Science and Technology Forum
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302009/ https://www.ncbi.nlm.nih.gov/pubmed/28239629 http://dx.doi.org/10.7603/s40782-014-0017-6 |