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Troponin Mutation Caused Diastolic Dysfunction and Experimental Treatment in Transgenic Mice with Cardiomyopathy

Troponin, a contractile protein of the thin filament of striated muscle, consists of three subunits: troponin C (TnC), troponin T (TnT), and troponin I (TnI). Cardiac troponin I (cTnI) plays a critical role in regulation of cardiac function. The physiological effect of cTnI, as an inhibitory subunit...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Tian, Jie, Huang, Xupei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Global Science and Technology Forum 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302009/
https://www.ncbi.nlm.nih.gov/pubmed/28239629
http://dx.doi.org/10.7603/s40782-014-0017-6