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PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?

The first clinical description of Parkinson’s disease (PD) will embrace its two century anniversary in 2017. For the past 30 years, mitochondrial dysfunction has been hypothesized to play a central role in the pathobiology of this devastating neurodegenerative disease. The identifications of mutatio...

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Detalles Bibliográficos
Autores principales: Truban, Dominika, Hou, Xu, Caulfield, Thomas R., Fiesel, Fabienne C., Springer, Wolfdieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302033/
https://www.ncbi.nlm.nih.gov/pubmed/27911343
http://dx.doi.org/10.3233/JPD-160989