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PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?
The first clinical description of Parkinson’s disease (PD) will embrace its two century anniversary in 2017. For the past 30 years, mitochondrial dysfunction has been hypothesized to play a central role in the pathobiology of this devastating neurodegenerative disease. The identifications of mutatio...
Autores principales: | Truban, Dominika, Hou, Xu, Caulfield, Thomas R., Fiesel, Fabienne C., Springer, Wolfdieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302033/ https://www.ncbi.nlm.nih.gov/pubmed/27911343 http://dx.doi.org/10.3233/JPD-160989 |
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