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Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A

Dysregulation of Wnt/β-catenin signaling has been associated with the development and progression of many cancers. The stability and subcellular localization of β-catenin, a dual functional protein that plays a role in intracellular adhesion and in regulating gene expression, is tightly regulated. H...

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Detalles Bibliográficos
Autores principales: Persad, Amit, Venkateswaran, Geetha, Hao, Li, Garcia, Maria E., Yoon, Jenny, Sidhu, Jaskiran, Persad, Sujata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302038/
https://www.ncbi.nlm.nih.gov/pubmed/28191283
http://dx.doi.org/10.18632/genesandcancer.128