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Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A
Dysregulation of Wnt/β-catenin signaling has been associated with the development and progression of many cancers. The stability and subcellular localization of β-catenin, a dual functional protein that plays a role in intracellular adhesion and in regulating gene expression, is tightly regulated. H...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302038/ https://www.ncbi.nlm.nih.gov/pubmed/28191283 http://dx.doi.org/10.18632/genesandcancer.128 |