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ABCA1 Deficiency Affects Basal Cognitive Deficits and Dendritic Density in Mice

ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins and regulates the generation of high density lipoproteins. Previously, we have shown that lack of Abca1 significantly increases amyloid deposition and cognitive deficits in Alzheimer’s disease model...

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Detalles Bibliográficos
Autores principales: Fitz, Nicholas F., Carter, Alexis Y., Tapias, Victor, Castranio, Emilie L., Kodali, Ravindra, Lefterov, Iliya, Koldamova, Radosveta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302049/
https://www.ncbi.nlm.nih.gov/pubmed/28106559
http://dx.doi.org/10.3233/JAD-161056