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Mass spectral determination of phosphopantetheinylation specificity for carrier proteins in Mycobacterium tuberculosis
Phosphopantetheinyl transferases (PPTases) are key elements in the modular syntheses performed by multienzyme systems such as polyketide synthases. PPTases transfer phosphopantetheine derivatives from Coenzyme A to carrier proteins (CPs), thus orchestrating substrate supply. We describe an efficient...
Autores principales: | Jung, James, Bashiri, Ghader, Johnston, Jodie M., Baker, Edward N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302061/ https://www.ncbi.nlm.nih.gov/pubmed/28203522 http://dx.doi.org/10.1002/2211-5463.12140 |
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