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Virtual Screening of DrugBank Reveals Two Drugs as New BCRP Inhibitors
The breast cancer resistance protein (BCRP) is an ABC transporter playing a crucial role in the pharmacokinetics of drugs. The early identification of substrates and inhibitors of this efflux transporter can help to prevent or foresee drug-drug interactions. In this work, we built a ligand-based in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302078/ https://www.ncbi.nlm.nih.gov/pubmed/27401583 http://dx.doi.org/10.1177/1087057116657513 |