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EGFR targeted therapy in lung cancer; an evolving story

Specific oncogenes with driver mutations, such as the Epidermal Growth Factor Receptor (EGFR 1) gene can lead to non-small-cell lung cancer formation. Identification of these oncogenes, their driver mutations and downstream effects allow the targeting of these pathways by drugs. Such personalised th...

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Detalles Bibliográficos
Autores principales: Bartholomew, C., Eastlake, L., Dunn, P., Yiannakis, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302182/
https://www.ncbi.nlm.nih.gov/pubmed/28217439
http://dx.doi.org/10.1016/j.rmcr.2017.01.016