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Structural coalescence underlies the aggregation propensity of a β-barrel protein motif

A clear understanding of the structural foundations underlying protein aggregation is an elusive goal of central biomedical importance. A step toward this aim is exemplified by the β-barrel motif represented by the intestinal fatty acid binding protein (IFABP) and two abridged all-β sheet forms (Δ98...

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Detalles Bibliográficos
Autores principales: Angelani, Carla R., Caramelo, Julio J., Curto, Lucrecia M., Delfino, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302452/
https://www.ncbi.nlm.nih.gov/pubmed/28187186
http://dx.doi.org/10.1371/journal.pone.0170607