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Structural coalescence underlies the aggregation propensity of a β-barrel protein motif
A clear understanding of the structural foundations underlying protein aggregation is an elusive goal of central biomedical importance. A step toward this aim is exemplified by the β-barrel motif represented by the intestinal fatty acid binding protein (IFABP) and two abridged all-β sheet forms (Δ98...
Autores principales: | Angelani, Carla R., Caramelo, Julio J., Curto, Lucrecia M., Delfino, José M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302452/ https://www.ncbi.nlm.nih.gov/pubmed/28187186 http://dx.doi.org/10.1371/journal.pone.0170607 |
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