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Degradable Dextran Nanopolymer as a Carrier for Choline Kinase (ChoK) siRNA Cancer Therapy

Although small interfering RNA (siRNA) therapy has proven to be a specific and effective treatment in cells, the delivery of siRNA is a challenge for the applications of siRNA therapy. We present a degradable dextran with amine groups as an siRNA nano-carrier. In our nano-carrier, the amine groups a...

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Detalles Bibliográficos
Autores principales: Chen, Zhihang, Krishnamachary, Balaji, Bhujwalla, Zaver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302479/
https://www.ncbi.nlm.nih.gov/pubmed/28344291
http://dx.doi.org/10.3390/nano6020034