Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization

Recently, the use of mammalian target of rapamycin (mTOR) inhibitors, in particular rapamycin (Rp), has been suggested to improve the treatment of neurodegenerative diseases. However, as Rp is a strong immunosuppressant, specific delivery to the brain has been postulated to avoid systemic exposure....

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Detalles Bibliográficos
Autores principales: Polchi, Alice, Magini, Alessandro, Mazuryk, Jarosław, Tancini, Brunella, Gapiński, Jacek, Patkowski, Adam, Giovagnoli, Stefano, Emiliani, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302501/
https://www.ncbi.nlm.nih.gov/pubmed/28335215
http://dx.doi.org/10.3390/nano6050087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302501/
https://www.ncbi.nlm.nih.gov/pubmed/28335215
http://dx.doi.org/10.3390/nano6050087

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