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Targeted Sterically Stabilized Phospholipid siRNA Nanomedicine for Hepatic and Renal Fibrosis

Since its discovery, small interfering RNA (siRNA) has been considered a potent tool for modulating gene expression. It has the ability to specifically target proteins via selective degradation of messenger RNA (mRNA) not easily accessed by conventional drugs. Hence, RNA interference (RNAi) therapeu...

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Detalles Bibliográficos
Autores principales: Khaja, Fatima, Jayawardena, Dulari, Kuzmis, Antonina, Önyüksel, Hayat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302539/
https://www.ncbi.nlm.nih.gov/pubmed/28344266
http://dx.doi.org/10.3390/nano6010008