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Effects of Particle Hydrophobicity, Surface Charge, Media pH Value and Complexation with Human Serum Albumin on Drug Release Behavior of Mitoxantrone-Loaded Pullulan Nanoparticles

We prepared two types of cholesterol hydrophobically modified pullulan nanoparticles (CHP) and carboxyethyl hydrophobically modified pullulan nanoparticles (CHCP) substituted with various degrees of cholesterol, including 3.11, 6.03, 6.91 and 3.46 per polymer, and named CHP(−3.11), CHP(−6.03), CHP(−...

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Detalles Bibliográficos
Autores principales: Tao, Xiaojun, Jin, Shu, Wu, Dehong, Ling, Kai, Yuan, Liming, Lin, Pingfa, Xie, Yongchao, Yang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302549/
https://www.ncbi.nlm.nih.gov/pubmed/28344259
http://dx.doi.org/10.3390/nano6010002