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Effects of Particle Hydrophobicity, Surface Charge, Media pH Value and Complexation with Human Serum Albumin on Drug Release Behavior of Mitoxantrone-Loaded Pullulan Nanoparticles
We prepared two types of cholesterol hydrophobically modified pullulan nanoparticles (CHP) and carboxyethyl hydrophobically modified pullulan nanoparticles (CHCP) substituted with various degrees of cholesterol, including 3.11, 6.03, 6.91 and 3.46 per polymer, and named CHP(−3.11), CHP(−6.03), CHP(−...
Autores principales: | Tao, Xiaojun, Jin, Shu, Wu, Dehong, Ling, Kai, Yuan, Liming, Lin, Pingfa, Xie, Yongchao, Yang, Xiaoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302549/ https://www.ncbi.nlm.nih.gov/pubmed/28344259 http://dx.doi.org/10.3390/nano6010002 |
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