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Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands

The extracellular matrix (ECM) is abnormal in breast tumors and has been reported to contribute to breast tumor progression. One factor, which may drive ongoing matrix synthesis in breast tumors, is the loss of stromal caveolin-1 (cav-1), a scaffolding protein of caveolae, which has been linked to b...

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Detalles Bibliográficos
Autores principales: Thompson, Christopher, Rahim, Sahar, Arnold, Jeremiah, Hielscher, Abigail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302825/
https://www.ncbi.nlm.nih.gov/pubmed/28187162
http://dx.doi.org/10.1371/journal.pone.0172067