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Re-wiring of energy metabolism promotes viability during hyperreplication stress in E. coli
Chromosome replication in Escherichia coli is initiated by DnaA. DnaA binds ATP which is essential for formation of a DnaA-oriC nucleoprotein complex that promotes strand opening, helicase loading and replisome assembly. Following initiation, DnaA(ATP) is converted to DnaA(ADP) primarily by the Regu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302844/ https://www.ncbi.nlm.nih.gov/pubmed/28129339 http://dx.doi.org/10.1371/journal.pgen.1006590 |