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Re-wiring of energy metabolism promotes viability during hyperreplication stress in E. coli

Chromosome replication in Escherichia coli is initiated by DnaA. DnaA binds ATP which is essential for formation of a DnaA-oriC nucleoprotein complex that promotes strand opening, helicase loading and replisome assembly. Following initiation, DnaA(ATP) is converted to DnaA(ADP) primarily by the Regu...

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Detalles Bibliográficos
Autores principales: Charbon, Godefroid, Campion, Christopher, Chan, Siu Hung Joshua, Bjørn, Louise, Weimann, Allan, da Silva, Luís Cláudio Nascimento, Jensen, Peter Ruhdal, Løbner-Olesen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302844/
https://www.ncbi.nlm.nih.gov/pubmed/28129339
http://dx.doi.org/10.1371/journal.pgen.1006590

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