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α(2)-adrenoreceptor modulated FAK pathway induced by dexmedetomidine attenuates pulmonary microvascular hyper-permeability following kidney injury

Renal ischemia-reperfusion (rI/R) could cause remote acute lung injury (ALI) and combination of these two organ injuries can remarkably increase the mortality. This study aims to determine whether dexmedetomidine, an α(2)-adrenoreceptor agonist sedative, can ameliorate pulmonary microvascular hyper-...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Yi, Bin, Ma, Jianbo, Ning, Jiaoling, Wu, Lingzhi, Ma, Daqing, Lu, Kaizhi, Gu, Jianteng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302891/
https://www.ncbi.nlm.nih.gov/pubmed/27463003
http://dx.doi.org/10.18632/oncotarget.10809