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Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche

Multiple myeloma cell growth relies on intrinsic aggressiveness, due to a high karyotypic instability, or on the support from bone marrow (BM) niche. We and other groups have provided evidences that Notch signaling is related to tumor cell growth, pharmacological resistance, localization/recirculati...

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Detalles Bibliográficos
Autores principales: Colombo, Michela, Galletti, Serena, Bulfamante, Gaetano, Falleni, Monica, Tosi, Delfina, Todoerti, Katia, Lazzari, Elisa, Crews, Leslie A., Jamieson, Catriona H.M., Ravaioli, Sara, Baccianti, Francesco, Garavelli, Silvia, Platonova, Natalia, Neri, Antonino, Chiaramonte, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302893/
https://www.ncbi.nlm.nih.gov/pubmed/27463014
http://dx.doi.org/10.18632/oncotarget.10820