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Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche
Multiple myeloma cell growth relies on intrinsic aggressiveness, due to a high karyotypic instability, or on the support from bone marrow (BM) niche. We and other groups have provided evidences that Notch signaling is related to tumor cell growth, pharmacological resistance, localization/recirculati...
Autores principales: | Colombo, Michela, Galletti, Serena, Bulfamante, Gaetano, Falleni, Monica, Tosi, Delfina, Todoerti, Katia, Lazzari, Elisa, Crews, Leslie A., Jamieson, Catriona H.M., Ravaioli, Sara, Baccianti, Francesco, Garavelli, Silvia, Platonova, Natalia, Neri, Antonino, Chiaramonte, Raffaella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302893/ https://www.ncbi.nlm.nih.gov/pubmed/27463014 http://dx.doi.org/10.18632/oncotarget.10820 |
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