Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133(+) tumor initiating cells

Chemoresistance in pancreatic cancer has been attributed to tumor-initiating cells (TICs), a minor sub-population of tumor cells. However, the mechanism of chemo-resistance in these cells is still unclear. In the current study, immunohistochemical analysis of LSL-Kras(G12D); LSL-Trp53(R172H;) PdxCre...

Descripción completa

Detalles Bibliográficos
Autores principales: Nomura, Alice, Dauer, Patricia, Gupta, Vineet, McGinn, Olivia, Arora, Nivedita, Majumdar, Kaustav, III, Charles Uhlrich, Dalluge, Joseph, Dudeja, Vikas, Saluja, Ashok, Banerjee, Sulagna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302917/
https://www.ncbi.nlm.nih.gov/pubmed/27472388
http://dx.doi.org/10.18632/oncotarget.10838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302917/
https://www.ncbi.nlm.nih.gov/pubmed/27472388
http://dx.doi.org/10.18632/oncotarget.10838

Ejemplares similares