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EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis

Polycomb group (PcG) proteins are highly conserved epigenetic effectors that maintain the silenced state of genes. EZH2 is the catalytic core and one of the most important components of the polycomb repressive complex 2 (PRC2). In non-small cell lung cancer (NSCLC) cells and primary lung tumors, we...

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Detalles Bibliográficos
Autores principales: Liu, Haidan, Li, Wei, Yu, Xinfang, Gao, Feng, Duan, Zhi, Ma, Xiaolong, Tan, Shiming, Yuan, Yunchang, Liu, Lijun, Wang, Jian, Zhou, Xinmin, Yang, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302918/
https://www.ncbi.nlm.nih.gov/pubmed/27472460
http://dx.doi.org/10.18632/oncotarget.10841