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Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin

In the present work we show that multiple lung cancer cell lines contain cisplatin resistant cell subpopulations expressing the Colony-Stimulating-Factor-Receptor-1 (CSF-1R) and surviving chemotherapy-induced stress. By exploiting siRNA-mediated knock down in vitro and the use of an investigational...

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Detalles Bibliográficos
Autores principales: Pass, Harvey I., Lavilla, Carmencita, Canino, Claudia, Goparaju, Chandra, Preiss, Jordan, Noreen, Samrah, Blandino, Giovanni, Cioce, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302923/
https://www.ncbi.nlm.nih.gov/pubmed/27486763
http://dx.doi.org/10.18632/oncotarget.10895