DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma

The RNAse III endonuclease DICER is a key regulator of microRNA (miRNA) biogenesis and is frequently decreased in a variety of malignancies. We characterized the role of DICER in glioblastoma (GB), specifically demonstrating its effects on the ability of glioma stem-like cells (GSCs) to form tumors...

Descripción completa

Detalles Bibliográficos
Autores principales: Mansouri, Sheila, Singh, Sanjay, Alamsahebpour, Amir, Burrell, Kelly, Li, Mira, Karabork, Merve, Ekinci, Can, Koch, Elizabeth, Solaroglu, Ihsan, Chang, Jeffery T., Wouters, Bradly, Aldape, Kenneth, Zadeh, Gelareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302925/
https://www.ncbi.nlm.nih.gov/pubmed/27421140
http://dx.doi.org/10.18632/oncotarget.10570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302925/
https://www.ncbi.nlm.nih.gov/pubmed/27421140
http://dx.doi.org/10.18632/oncotarget.10570

Ejemplares similares