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DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma

The RNAse III endonuclease DICER is a key regulator of microRNA (miRNA) biogenesis and is frequently decreased in a variety of malignancies. We characterized the role of DICER in glioblastoma (GB), specifically demonstrating its effects on the ability of glioma stem-like cells (GSCs) to form tumors...

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Detalles Bibliográficos
Autores principales:	Mansouri, Sheila, Singh, Sanjay, Alamsahebpour, Amir, Burrell, Kelly, Li, Mira, Karabork, Merve, Ekinci, Can, Koch, Elizabeth, Solaroglu, Ihsan, Chang, Jeffery T., Wouters, Bradly, Aldape, Kenneth, Zadeh, Gelareh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302925/ https://www.ncbi.nlm.nih.gov/pubmed/27421140 http://dx.doi.org/10.18632/oncotarget.10570

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