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[(64)Cu]XYIMSR-06: A dual-motif CAIX ligand for PET imaging of clear cell renal cell carcinoma

Carbonic anhydrase IX (CAIX) is a cell surface enzyme that is over-expressed in approximately 95% of cases of clear cell renal cell carcinoma (ccRCC), the most common renal cancer. We synthesized and performed in vitro and in vivo evaluation of a dual-motif ligand, [(64)Cu]XYIMSR-06, for imaging CAI...

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Detalles Bibliográficos
Autores principales: Minn, Il, Koo, Soo Min, Lee, Hye Soo, Brummet, Mary, Rowe, Steven P., Gorin, Michael A., Sysa-Shah, Polina, Lewis, William D., Ahn, Hye-Hyun, Wang, Yuchuan, Banerjee, Sangeeta Ray, Mease, Ronnie C., Nimmagadda, Sridhar, Allaf, Mohamad E., Pomper, Martin G., Yang, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302928/
https://www.ncbi.nlm.nih.gov/pubmed/27437764
http://dx.doi.org/10.18632/oncotarget.10602