Guttiferone K suppresses cell motility and metastasis of hepatocellular carcinoma by restoring aberrantly reduced profilin 1

Hepatocellular carcinoma (HCC) is an aggressive malignancy and the 5-year survival rate of advanced HCC is < 10%. Guttiferone K (GUTK) isolated from the Garcinia genus inhibited HCC cells migration and invasion in vitro and metastasis in vivo without apparent toxicity. Proteomic analysis revealed...

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Detalles Bibliográficos
Autores principales: Shen, Kaikai, Xi, Zhichao, Xie, Jianling, Wang, Hua, Xie, Chanlu, Lee, C.Soon, Fahey, Paul, Dong, Qihan, Xu, Hongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302942/
https://www.ncbi.nlm.nih.gov/pubmed/27494863
http://dx.doi.org/10.18632/oncotarget.10992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302942/
https://www.ncbi.nlm.nih.gov/pubmed/27494863
http://dx.doi.org/10.18632/oncotarget.10992

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