Inhibition of Mnk enhances apoptotic activity of cytarabine in acute myeloid leukemia cells

Cytarabine (Ara-C) is a first line clinical therapeutic agent for treatment of acute myeloid leukemia (AML). However, this therapy is limited due to high rate of resistance and relapse. Recent research has revealed that the poor prognosis and resistance to Ara-C in AML were associated with its abnor...

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Detalles Bibliográficos
Autores principales: Li, Peng, Diab, Sarah, Yu, Mingfeng, Adams, Julian, Islam, Saiful, Basnet, Sunita K.C., Albrecht, Hugo, Milne, Robert, Wang, Shudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302954/
https://www.ncbi.nlm.nih.gov/pubmed/27462781
http://dx.doi.org/10.18632/oncotarget.10796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302954/
https://www.ncbi.nlm.nih.gov/pubmed/27462781
http://dx.doi.org/10.18632/oncotarget.10796

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