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IGF-II induced by hepatitis B virus X protein regulates EMT via SUMO mediated loss of E-cadherin in mice

Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of cancer mortality. Prognosis of this disease largely depends on its stage. An Enlarged liver, due to dysplasia, may be a critical point in the multi-step progression to HCC. The mechanism underlying hepatomegaly i...

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Detalles Bibliográficos
Autores principales: Ha, Hye-Lin, Kwon, Taeho, Bak, In Seon, Erikson, Raymond L., Kim, Bo Yeon, Yu, Dae-Yeul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302964/
https://www.ncbi.nlm.nih.gov/pubmed/27486970
http://dx.doi.org/10.18632/oncotarget.10922