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A role for activated Cdc42 in glioblastoma multiforme invasion

Cdc42 is a Rho-GTPase which plays a major role in regulating cell polarity and migration by specifying the localization of filopodia. However, the role of Cdc42 in GBM invasion has not been thoroughly investigated. We generated stable doxycycline-inducible clones expressing wild type (WT)-, constitu...

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Detalles Bibliográficos
Autores principales: Okura, Hidehiro, Golbourn, Brian J., Shahzad, Uswa, Agnihotri, Sameer, Sabha, Nesrin, Krieger, Jonathan R., Figueiredo, Carlyn A., Chalil, Alan, Landon-Brace, Natalie, Riemenschneider, Alexandra, Arai, Hajime, Smith, Christian A., Xu, Songli, Kaluz, Stefan, Marcus, Adam I., Van Meir, Erwin G., Rutka, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302965/
https://www.ncbi.nlm.nih.gov/pubmed/27486972
http://dx.doi.org/10.18632/oncotarget.10925