Telomere status in chronic lymphocytic leukemia with TP53 disruption

In chronic lymphocytic leukemia (CLL), telomere dysfunction is associated with poor outcomes. TP53 is involved in cellular responses to dysfunctional telomeres, and its inactivation is the strongest adverse prognostic factor for CLL. Given the biological relationship between TP53 and telomeres, and...

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Detalles Bibliográficos
Autores principales: Guièze, Romain, Pages, Mélanie, Véronèse, Lauren, Combes, Patricia, Lemal, Richard, Gay-bellile, Mathilde, Chauvet, Martine, Callanan, Mary, Kwiatkowski, Fabrice, Pereira, Bruno, Vago, Philippe, Bay, Jacques-Olivier, Tournilhac, Olivier, Tchirkov, Andreï
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302966/
https://www.ncbi.nlm.nih.gov/pubmed/27486974
http://dx.doi.org/10.18632/oncotarget.10927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302966/
https://www.ncbi.nlm.nih.gov/pubmed/27486974
http://dx.doi.org/10.18632/oncotarget.10927

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