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Targeted deep sequencing improves outcome stratification in chronic myelomonocytic leukemia with low risk cytogenetic features

Clonal cytogenetic abnormalities are found in 20-30% of patients with chronic myelomonocytic leukemia (CMML), while gene mutations are present in >90% of cases. Patients with low risk cytogenetic features account for 80% of CMML cases and often fall into the low risk categories of CMML prognostic...

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Detalles Bibliográficos
Autores principales: Palomo, Laura, Garcia, Olga, Arnan, Montse, Xicoy, Blanca, Fuster, Francisco, Cabezón, Marta, Coll, Rosa, Ademà, Vera, Grau, Javier, Jiménez, Maria-José, Pomares, Helena, Marcé, Sílvia, Mallo, Mar, Millá, Fuensanta, Alonso, Esther, Sureda, Anna, Gallardo, David, Feliu, Evarist, Ribera, Josep-Maria, Solé, Francesc, Zamora, Lurdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302970/
https://www.ncbi.nlm.nih.gov/pubmed/27486981
http://dx.doi.org/10.18632/oncotarget.10937