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Coexistence of JAK2 and CALR mutations and their clinical implications in patients with essential thrombocythemia

Janus kinase 2 (JAK2) and calreticulin (CALR) constitute the two most frequent mutations in essential thrombocythemia (ET), and both are reported to be mutually exclusive. Hence, we examined a cohort of 123 myeloproliferative neoplasm (MPN) patients without BCR-ABL1 rearrangement and additional ET p...

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Detalles Bibliográficos
Autores principales: Kang, Min-Gu, Choi, Hyun-Woo, Lee, Jun Hyung, Choi, Yong Jun, Choi, Hyun-Jung, Shin, Jong-Hee, Suh, Soon-Pal, Szardenings, Michael, Kim, Hye-Ran, Shin, Myung-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302971/
https://www.ncbi.nlm.nih.gov/pubmed/27486987
http://dx.doi.org/10.18632/oncotarget.10958