DR5 mAb-conjugated, DTIC-loaded immuno-nanoparticles effectively and specifically kill malignant melanoma cells in vivo

We combined chemo- and immunotherapies by constructing dual therapeutic function immuno-nanoparticles (NPs) consisting of death receptor 5 monoclonal antibody (DR5 mAb)-conjugated nanoparticles loaded with dacarbazine (DTIC) (DTIC-NPs-DR5 mAb). We determined the in vivo targeting specificity of DTIC...

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Detalles Bibliográficos
Autores principales: Ding, Baoyue, Zhang, Wei, Wu, Xin, Wang, Jeffrey, Xie, Chen, Huang, Xuan, Zhan, Shuyu, Zheng, Yongxia, Huang, Yueyan, Xu, Ningyin, Ding, Xueying, Gao, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302980/
https://www.ncbi.nlm.nih.gov/pubmed/27494835
http://dx.doi.org/10.18632/oncotarget.11014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302980/
https://www.ncbi.nlm.nih.gov/pubmed/27494835
http://dx.doi.org/10.18632/oncotarget.11014

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