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Epimutational profile of hematologic malignancies as attractive target for new epigenetic therapies

In recent years, recurrent somatic mutations in epigenetic regulators have been identified in patients with hematological malignancies. Furthermore, chromosomal translocations in which the fusion protein partners are themselves epigenetic regulators or where epigenetic regulators are recruited/targe...

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Detalles Bibliográficos
Autores principales: Fratta, Elisabetta, Montico, Barbara, Rizzo, Aurora, Colizzi, Francesca, Sigalotti, Luca, Dolcetti, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302993/
https://www.ncbi.nlm.nih.gov/pubmed/27329599
http://dx.doi.org/10.18632/oncotarget.10033