Benzenesulphonamide inhibitors of the cytolytic protein perforin

The pore-forming protein perforin is a key component of mammalian cell-mediated immunity and essential to the pathway that allows elimination of virus-infected and transformed cells. Perforin activity has also been implicated in certain auto-immune conditions and therapy-induced conditions such as a...

Descripción completa

Detalles Bibliográficos
Autores principales: Spicer, Julie A., Miller, Christian K., O'Connor, Patrick D., Jose, Jiney, Huttunen, Kristiina M., Jaiswal, Jagdish K., Denny, William A., Akhlaghi, Hedieh, Browne, Kylie A., Trapani, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303009/
https://www.ncbi.nlm.nih.gov/pubmed/28110869
http://dx.doi.org/10.1016/j.bmcl.2016.12.057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303009/
https://www.ncbi.nlm.nih.gov/pubmed/28110869
http://dx.doi.org/10.1016/j.bmcl.2016.12.057

Ejemplares similares