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Benzenesulphonamide inhibitors of the cytolytic protein perforin

The pore-forming protein perforin is a key component of mammalian cell-mediated immunity and essential to the pathway that allows elimination of virus-infected and transformed cells. Perforin activity has also been implicated in certain auto-immune conditions and therapy-induced conditions such as a...

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Detalles Bibliográficos
Autores principales:	Spicer, Julie A., Miller, Christian K., O'Connor, Patrick D., Jose, Jiney, Huttunen, Kristiina M., Jaiswal, Jagdish K., Denny, William A., Akhlaghi, Hedieh, Browne, Kylie A., Trapani, Joseph A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Ltd 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303009/ https://www.ncbi.nlm.nih.gov/pubmed/28110869 http://dx.doi.org/10.1016/j.bmcl.2016.12.057

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