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Naturally occurring anti-glycan antibodies binding to Globo H-expressing cells identify ovarian cancer patients

BACKGROUND: Glycosphingolipids are important compounds of the plasma membrane of mammalian cells and a number of them have been associated with malignant transformation and progression, reinforcing tumour aggressiveness and metastasis. Here we investigated the levels of naturally occurring anti-glyc...

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Detalles Bibliográficos
Autores principales: Pochechueva, Tatiana, Alam, Shahidul, Schötzau, Andreas, Chinarev, Alexander, Bovin, Nicolai V., Hacker, Neville F., Jacob, Francis, Heinzelmann-Schwarz, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303257/
https://www.ncbi.nlm.nih.gov/pubmed/28187738
http://dx.doi.org/10.1186/s13048-017-0305-8